The Cure Starts Now Shines Bright for Childhood Brain Cancer Research
CINCINNATI, OH | April 15 — On a night full of glitter, glam, and game show excitement, the Cincinnati community once again proved just how powerful it can be when united for a cause. The 18th annual Once in a Lifetime Gala, presented by Graeter’s, brought over 900 people together in dazzling style to support one mission: ending childhood brain cancer.
More than just an auction and fundraiser, the event brought together supporters and families whose children have battled brain cancer, honoring more than 60 kids from across the country in a powerful celebration of hope for a brighter future. From laughter-filled moments to heartfelt tributes, the evening struck a perfect balance between joy and purpose.
Thanks to the generosity and passion of everyone involved, an incredible $775,000 was raised for childhood brain cancer research and support. This money will fuel hope, advance research, and bring us closer than ever to a world without cancer.
"We have hope that one day we will find a cure for brain cancer. No kids fight alone, and we won't stop funding research until all kids have the chance to be cancer-free," said guest speaker, Amanda Thomas, and mom to 6-year-old Wyatt battling brain cancer.

A highlight of the night was the presentation of the Changemaker Award, a powerful tribute to four remarkable individuals whose unwavering dedication has helped move the needle in the fight for the Homerun Cure™. Whether they’re promoting events, volunteering their time, or taking the mic as emcees, Rani Rico, Brian Thomas, Amanda Orlando, and Tommy Palmer exemplify what it means to go above and beyond to honor the legacies of our kids.
Inspired by the incredible Lauren Hill, a Cincinnati legend who captured the nation’s heart with her love of basketball and her courageous fight for a cure for brain cancer, the Full Court Press Award honors individuals who go beyond raising awareness to drive real, impactful change in cancer research.
We were proud to present this prestigious award to Indiana Governor Mike Braun for his tireless efforts in advancing the Promising Pathways Act, a critical bill that has the potential to fast-track life-saving treatments for children facing terminal and rare diseases. Every child deserves a promising pathway to treatment, and Senator Braun’s leadership is helping turn that hope into a reality.
Reflecting upon the event, co-founder and CEO, Brooke Desserich commented,
“Every single person in that room is helping change how our kids fight cancer. I am incredibly grateful for the love, generosity, and commitment of this amazing community.”
A heartfelt thank you goes out to our generous sponsors who made this unforgettable evening possible: Graeter’s Ice Cream, Cincinnati Children’s, The Party Source, Abstract Displays, Bruce and Nancy Axmacher, Cincinnati Santacon, and The Hyde Park Blast. Their commitment and generosity fuel the fight and inspire hope in every child, every family, and every researcher on the front lines.
Watch the powerful story of two Wyatts in the Cincinnati area battling the same diagnosis and the bond it has created: