The Cure Starts Now has funded $21,188,327 in pediatric brain cancer research in partnership with the DIPG / DMG Collaborative. This includes 132 grants at over 100 hospitals in 17 countries.




Hospital for Sick Children - $50,000

Amount
$50,000.00
Date
September 2016

MRI Guided Focused Ultrasound: Targeted Drug Delivery in Diffuse Intrinsic Pontine Glioma

Gustave Roussy Cancer Center - $93,071

Amount
$93,071.00
Date
September 2016

Ultrasound-induced delivery of Panobinostat in preclinical models

The Hospital for Sick Children - $194,260

Amount
$194,260.00
Date
September 2016

Exploring the interactome of H3K27M to find therapeutic targets for DIPG

Cold Spring Harbor Laboratory - $100,000

Amount
$100,000.00
Date
September 2016

Allele-specific antisense therapy for DIPG

Children's Cancer Institute - $143,884

Amount
$143,884.00
Date
September 2016

Radiosensitisation of Diffuse Intrinsic Pontine Gliomas by modulating the glucose metabolism

Dana-Farber Cancer Institute - $100,000

Amount
$100,000.00
Date
December 2015

Characterizing resistance mechanisms to radiation therapy and adjuvant chemotherapy in Diffuse Intrinsic Pontine Glioma

Cincinnati Children's Hospital Medical Center - $100,000

Amount
$100,000.00
Date
December 2015

An early Phase 2 Study of LEE011, a CDK4/6 Inhibitor, following radiation therapy in Children with Newly Diagnosed non-biopsied Diffuse Pontine Gliomas (DIPG) and Rb+ biopsied DIPG and High Grade Gliomas (HGG)

Baylor College of Medicine/Texas Children's Hospital - $200,000

Amount
$200,000.00
Date
December 2015

Targeting DIPGs through Super-activation of Steroid Receptor Co-activators: An in vivo Study in Patient-derived Intra-brain Stem Xenograft Mouse Models

Children's National Health System and Children's Research Institute - $125,000

Amount
$125,000.00
Date
December 2015

Comprehensive Molecular-Based Cross-Species Comparison of DIPG Biology

Boston Children's Hospital - $110,000

Amount
$110,000.00
Date
December 2015

Enabling epigenetic therapies by exploring DIPG chromatin sensitivities

UCL Institute of Child Health - $200,000

Amount
$200,000.00
Date
December 2015

T-cell based immunotherapy for DIPG.

Dana Farber Cancer Institute - $100,000

Amount
$100,000.00
Date
December 2015

Discovering novel epigenetic dependencies in Diffuse Intrinsic Pontine Glioma

VU University Medical Center - $92,950

Amount
$92,950.00
Date
November 2015

Liquid Biopsies for the Monitoring of Diffuse Intrinsic Pontine Glioma.

Children's Cancer Institute - $145,341

Amount
$145,341.00
Date
November 2015

Fenretinide, a novel agent targeting RTK/PI3K/AKT network for the treatment of Diffuse Intrinsic Pontine Glioma.

Cincinnati Children's Hospital Medical Center - $200,000

Amount
$200,000.00
Date
October 2015

Intra-tumoral heterogeneity in diffuse intrinsic pontine and midline high-grade gliomas